Methylene Diphenyl Diisocyanate

Methylene Diphenyl Diisocyanate                                                                                      

Chemical Formula : C15H10N2O2                CAS Registry Number 101-68-8

Methyl di-p-phenylene isocyanate (MDI) is mainly used in polyurethane foams, which account for about 80% of global consumption. Rigid foams are mostly used in construction, refrigeration, packaging and insulation. MDI is also used to make binders, elastomers, adhesives, sealants and coatings.The positions of the isocyanate groups influences their reactivities. 4,4'-MDI is a symmetrical molecule and thus has two groups of equal reactivity. 2,4'-MDI is an asymmetrical molecule and thus has two groups of different reactivities. The group at the 4-position is approximately four times more reactive than the group at the 2-position.
Chemical Shapes MDI's Molecules



R-phrases: R20, R36/37/38, R42/43

S-phrases: (S1/2), S23, S36/37, S45


Storage and Handling                           

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The major application of 4,4'-MDI is the production of rigid polyurethane. Typically, one tonne of polyurethane foam needs 0.616 tonne of MDI and 0.386 tonne of polyol, with 0.054 tonne pentane as a blowing agent.   These rigid polyurethane foams are good thermal insulators and used in nearly all freezers and refrigerators worldwide, as well as buildings. Typical polyols used are polyethylene adipate (a polyester) and poly(tetramethylene ether) glycol (a polyether).4,4'-MDI is also used as an industrial strength adhesive, which is available to end consumers as various high-strength bottled glue preparations.



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