ISOPHORONE (C9H140)                                            

Isophorone can be manufactured by catalyzed self-condensation of acetone. Mesityl oxide is the initial product of the self-aldol condensation of acetone. The mesityl oxide formed can react further with acetone via a Michael reaction and subsequent intramolecular aldol condensation to eventually obtain the six-membered ring of isophorone. This is an example of the Robinson annulation. The yield of the two compounds depends on the reaction conditions.



Isophorone used as an intermediate in manufacturing mainly polyurethane field compounds such as Isophorone Diamine, Isophorone Diisocyanate, Trimethylcyclohexanone used for light-stable, weather-resistant urethane coatings. It is used as a solvent for in resins, lacquers and inks. It is used in formulating pesticides.


Storage and Handling

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Hazard :

NFPA 704

EU Classification

Risk Phrases: 21-36/37/38
Safety Phrases: 26


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